有关新药dexpramipexole的最新消息

navix · 发表于 2013-1-3 22:28:53

本帖最后由 navix 于 2013-1-3 22:37 编辑

dexpramipexole是目前最接近上市的新药，今年年初第三期第一次临床试验将有结果出来。今天在网上看到报道：

According to Bloomberg, Biogen's experimental drug for amyotrophic lateral sclerosis, dexpramipexole, failed to help patients in a clinical trial.

Read more: http://www.minyanville.com/trading-and-investing/stocks/articles/Biogen-and-Powershares-QQQ-Trust-Among/1/3/2013/id/47102#ixzz2GvDma7vv

该报道没有实验结果的具体内容，但说开发新药的公司Biogen因dexpramipexole实验无疗效，公司股票下跌6.5%。

仅供关注新药的朋友参考。

liangch · 发表于 2013-1-3 23:41:19

我想哭

navix · 发表于 2013-1-4 03:34:02

虽然Biogen的股票很快在一天内就止跌回头了，但有关新药Dex无疗效的消息还是被Biogen公司证实了：

The Phase 3 trial did not meet its primary endpoint, which was a joint rank analysis of function and survival, and no efficacy was seen in the individual components of function or survival. The trial also failed to show efficacy in its key secondary endpoints.
In a further blow to the company, a closer look at subgrgroups of patients also failed to show efficacy.
“We share the disappointment of members of the ALS community, who had hoped that would offer a meaningful new treatment option,” Douglas E. Williams, Biogen’s Executive Vice President of Research and Development, said in a statement. “Nevertheless, the Empower trial represents a significant contribution to ALS research, and Biogen Idec is committed to advancing ALS science. We continue to work with researchers around the world to understand the causes of ALS and find potential treatments for people with ALS.”
Biogen announced last month that it would commit $10 million to a new research consortium targeting ALS, and mentioned it has multiple early-stage drug candidates in the works. Conspicuously absent from the announcement was any mention of the Dex program.

不逐字翻译了。大意是新药Dex的第三期实验没有达到改善功能和延长寿命的效果。负责研发的副总裁对此表示致歉，但表示该实验对ALS的药物研发仍然有很大贡献。Biogen 公司不放弃对ALS病因和治疗方法的继续研发（上个月Biogen公布了向ALS研发团队注资一千万美元的计划），目前仍有多个新药在研发中，但Biogen 公司没有明确说明Dex计划的前途。

上善若水 · 发表于 2013-1-4 08:06:46

天很冷！

青松 · 发表于 2013-1-4 08:16:28

淡然

雨涵 · 发表于 2013-1-4 09:03:45

谢谢navix 分享

风云变幻 · 发表于 2013-1-4 09:19:35

w无言的结局，:'(

602380327 · 发表于 2013-1-4 09:21:19

:(:hug:

勿诚非扰 · 发表于 2013-1-4 09:32:27

失败是成功之母，会有希望的

孤独浪子 · 发表于 2013-1-4 10:18:47

:L

仰望生命 · 发表于 2013-1-4 11:07:02

顺乎天意

紫风飘絮 · 发表于 2013-1-4 11:36:38

心好寒啊:'(:'(:'(

sszgl168 · 发表于 2013-1-4 11:53:09

每天看到失败的消息，谁说不是积极信号?好过泱泱大国经年累月屁都不放一个强多了吧。

飘雪逗逗 · 发表于 2013-1-4 12:42:42

无论怎样，谢谢分享

超级光子 · 发表于 2013-1-4 13:38:28

希望会有的!

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